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Optimizing on Alkaline Hydrolysis and Organic Solvent Extract of Lignans from Schisandra Chinensis extract.

Date:2016/9/23 21:07:38

Optimizing on Alkaline Hydrolysis and Organic Solvent Extract of Lignans from Schisandra Chinensis extract.

Extracting the lignans from Schisandra Chinensis extract by 80% Ethanol.The effect of hydrolysis catalyzer 

was investigated and sodium hydroxide was the optimum catalyzer.The optimal operating conditions are obtained:

1 mol/L sodium hydroxide 15mL,reflexing extraction 2 h with 100 ℃.Then compared the extractive effect of 

chloroform,1,2-chloroethene,ethyl acetate and petroleum ether and determined that 1,2-chloroethene was the 

solvent of extraction in 70% ethanol.


The total lignans content of schizandrin,schisantherin A,deoxyschizandrin and γ-schizandrin from the fruit 

of Schisandra Chinensis extract increased from original 150.42,44.02,248.30 and 514.29 mg/kg to 455.96,58.21,

397.69 and 772.09 mg/kg respectively.The recycle of the total lignans gets to 165.91%.