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BIOLOGICALLY ACTIVE COMPOSITIONS FROM Schisandra chinensis extract FOR TREATING COLORECTAL CANCER

Date:2016/9/21 22:46:39

BIOLOGICALLY ACTIVE COMPOSITIONS FROM Schisandra chinensis extract FOR TREATING COLORECTAL CANCER. A biologically 

active composition to treat colorectal cancer includes an extract of the plant Schisandra chinensis extract and 

a suitable pharmaceutical formulation. The extract can be at least one of gomisin A, angeloylgomisin H, deoxyschisandrin 

and gomisin N, showing activities against human tumor cell line HT-29 in the range of about 716M to about 43M. 


A suitable pharmaceutical formulation can be any one of a pill, a tablet, a capsule, a liquid solution, a liquid 

suspension, a powder, an intravenous solution, a gel and a suppository form. The extract is prepared by grinding 

the dried berries, extracting with hexane, extracting the marc with dichloromethane, extracting the dichloromethane 

soluble fraction with ethyl acetate, removing fatty materials in the dichloromethane-ethyl acetate soluble fraction 

with hexane, and fractionating the total hexane insoluble material extract using analytical high performance 

liquid chromatography equipped with automated repeat injection/collection cycles.