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The influence of extract of schisandra chinensis extract and paeonia veitchii on the level of cytokines in serum of asthmatic rats

Date:2016/9/13 23:21:07

The influence of extract of schisandra chinensis extract and paeonia veitchii on the level of cytokines in 

serum of asthmatic rats. Objective To investigate the influence of extract of schisandra chinensis extract 

and paeonia veitchii on level of cytokines in asthmatic rats.Methods SD rats were randomly divided into three 

groups:Chinese medicine-treated,untreated asthma,physiological saline control groups.The tracheal pathology 

and symptom of different groups were observed,then cytokine expressions in serum were detected with enzyme-

linked immunosorbent assay(ELISA).Results Chinese herb extract obviously improved tracheal pathology and airway 

symptoms.The levels of IL-4,IL-6、IL-13in serum of Chinese medicine-treated and untreated asthma groups were 

significantly increased,while the IFN-γexpression was reduced.But after treatment of Chinese herb extract,

compared with untreated asthma group the IFN-γexpression was significantly increased in Chinese medicine-

treated group.Conclusion The effect of schisandra chinensis extract and paeonia veitchii could reduce airway 

inflammation of asthma rats may by significantly increased IFN-γexpression.